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Therefore, the spatial arrangements induced by EA and MDSA lead to the loss of divalent ion at the active site and inhibit catalysis

The overall incident rates for the control and case groups are about $6\%$ and $18.5\%$, which are $-2.75$ and $-1.48$ on a logit scale equivalently

Chemotactic factors such as CCR5 recruit inflammatory factors including interleukin (IL)-1, IL-6, macrophage migration inhibitory factor, and high mobility group box 1 protein (HMGB1), which accumulate around the vessels

This study highlights the potential of enzyme-mimicking nanomaterials in replicating multifunctional enzyme activity and supports material-based strategies for targeting cancer metabolism